CRISPR Gene Editing Technique Used In Creating HIV Immune Twin Sisters

Chinese medical officials are investigating the scientist who claims to have created the world’s first genetically-edited babies. He Jiankui said the twin sisters were born with immunity to HIV, the virus that causes AIDS. He claims he altered their DNA in a lab using a gene editing technique called CRISPR.

The controversial research was roundly condemned because it was shrouded in secrecy and broke with international scientific norms. But He said his breakthrough can protect children from a dangerous and deadly disease, and that he’s on the right side of history.

The technology to genetically edit human embryos has been around for a while, but scientists were unwilling to cross that ethical line. He, a Stanford and Rice University trained physicist, said he used the technique CRISPR to help a married Chinese couple conceive twins immune to HIV.

“I believe families need this technology. And I’m willing to take the criticism for them,” He said.

When the girls were still embryos, he used chemical “scissors” to turn off a gene that makes people vulnerable to HIV infection. The embryos were then implanted into the mother who gave birth to Lulu and Nana earlier this month.

“No gene was changed except the one to prevent HIV infection. The girls are safe, healthy as any other babies,” He said.

China’s National Health Commission ordered an investigation into He’s work, which defied a global scientific consensus banning the use of genetic editing on human embryos.

He’s university in China, where he was on unpaid leave, said it was “deeply shocked” by his research, which it believes “seriously violated academic ethics and codes of conduct.”

Kiran Musunuru, an associate professor of medicine at the University of Pennsylvania, believes this was an attempt to engineer genetically modified human beings.

“I think this was irresponsible,” Musunuru said. “No question that that is unethical. I would actually add immoral to that.”

Musunuru reviewed some of he’s scientific data and said he believes the genetic edits on the embryos were incomplete, meaning the girls may not be totally immune to HIV. Musunuru also said there’s evidence other genes were edited unintentionally, potentially increasing the twins’ risk for cancer.

“Taking those embryos forward through pregnancy to live children, to me, is absolutely appalling and horrifying. I can’t imagine why anyone with any sort of compassion would actually do that,” Musunuru said.

He will formally present his findings Wednesday at a scientific conference in Hong Kong. Rice University said the work described violates conduct guidelines of the scientific community and launched an ethics investigation into Michael Deem, a bioengineering professor who was part of He’s research team.

There are rules against this kind of experimentation in the U.S. and Europe, but not in China. The hope is the strong reaction from the scientific community, coupled with various investigations that have been opened, can be a deterrent.

Reference

Global outrage after Chinese researcher claims first gene-edited babies

Chinese Scientist Defends Creating Gene Edited Twin Sisters

What is Balinese massage & its advatnage

Balinese massage is a type of massage most people want to take. In today’s world massage is the most important thing for everybody. Because taking massage is the good for your body and health.

Good spa techniques are really hard to find. Only few of the massage centers providing good spa treatments. Many of the people don’t know about benefits of massage. There are plenty of benefits are available. Hope you can read this full article to know about what is Balinese massage & its advantages.

Balinese massage consist of lots of massage technique including acupuncture massage, reflexology, Thai & Aromatherapy.

Skin rolling, Stroking, Kneading, Pressure point stimulation combined with aromatherapy is called Balinese massage.

I already told this massage has plenty of benefits. By giving good amount of pressure and other massage technique, the Balinese massage done correctly.

I hope everybody knows what is full body massage. If you are don’t know visit Bangbodyspa for knowing full body massage service.

This is the service contains every massage technique. Likewise Balinese massage also consist of many massage types. That is why it is very effective for all kinds of people.

This massage has plenty of benefits those are:

It reduces body pain

It removes toxin from your skin

It eliminates bad things from your body

It purifies your blood

It stimulates high blood flow

It increase the immune

These are some major benefits of Balinese massage. Hope everybody get this massage, If you want to know more about Balinese massage then visit this page.

 

Amoveo Spa Review – The promising massage parlour

amoveo spa

When it comes to spa finding good spa is really hard. Many of the massage parlors are spamming their customers and not giving good massage.

Only few of the names in the industry still holding some values. In this list we need to consider Amoveo Spa.

Amoveo spa is Bangalore based massage center which provides lots of massage services like Thai massage, Nuru massage, Sandwich, Swedish, Aromatherapy and more.

Here we are going to see the review of Amoveo spa.

Quality of the massage:

Quality wise they are best in this business. Because many of the spa persons don’t have good quality materials, rooms and staffs. But in Amoveo you can find everything good.

They are using only premium oil and creams to massage client body. All are imported and their massage cabin is neat and clean. That is want every client want.

Service:

They are having 30+ masseurs in their spa. All are trained by Amoveo spa training academy. After getting certificate only they are allowed to massage clients. So, service quality is really awesome.

All trained staffs are good looking, clean and expert in body massage. That is why this spa remains number one massage center in Bangalore.

Price:

amoveo spa

You can see many of the parlours cost so much for massage. Especially if you are new in the city. But here you can see the affordable price chart.

You can also get Incall and outcall service from this massage center. The price differs from 500 to 2000 when you take outcall.

The straightforward price listing will help to know the details.

Safety & Security:

They provide excellent safety and security to their clients. They have cabs to pick and drop the customers. The safety wise they don’t reveal any information about you.

Overall Verdict:

So, come to the end of this review. At my point of view. Amoveo is best place to have some joy in the weekend. If you have time just visit their official website here. http://www.amoveospa.com/

Stay tuned with us for more health related reviews.

7 Health Hazards of Loneliness You Probably Didn’t Know

From everyday joes to experts, everyone talks how bad loneliness is. Even though there have been numerous reports, studies and experiments conducted which talk about the problems which are associated with being lonely, but the latest studies that came to the light shocked everyone. According to the latest studies, being lonely is 20% more deadlier than obesity. Besides, there is also another study which claimed that the negative impact of being isolated is equal to the negative impact of having 15 cigarettes in a single day.

Loneliness and Health Hazards

Everyone needs to understand that being lonely is determined by the person’s subjective quality and not by the quality or quantity of his/her relationship. And this is the reason why even after being surrounded by family members, colleagues/classmates and friends, a person still feels empty, unwanted, disconnected or in one word, lonely.

Currently we are living in a world where with the touch of the button you can get connected to another person; all thanks to smartphones, different social media sites and internet in general. But, it was revealed that even in today’s time about 30 to 40% of total population are in fact lonely, and may or is facing the health problems that comes with being lonely. Next we are going to go through the 7 different health hazards of loneliness that most people do not know about, but all of them are backed up by scientific and trusty reports and studies conducted by reputed experts on the subject.

  1. Raise of inflammation levels

Stress, worsen conditions of the symptoms of depression and anxiety are some of the commonly known problems associated with being lonely. According to a study it was discovered that being lonely definitely results in high levels of cortisol which will lead to chronic inflammation as well. According to an experiment conducted by the University of Ohio where the signs of inflammation was tracked, it was seen than a lonely person recovering from illness has difficulties because of the high level of cortisol than a person who is not lonely. The short-term healing response to an injury of the people) who are not lonely even under stress was better than a lonely person’s. Here it is important to add that the long term effects of chronic inflammation are diabetes and cancer.

  1. Lowered immune system

Besides rising the inflammation level, having high level of cortisol is associated with messing up of the immune system of a person as well. In simple words, because of high level of cortisol, the immune system gets a “shock” which lowers the capability of the body to heal quickly and properly. Besides, it also makes the person more venerable to different types of diseases as well. And this is why, people who are lonely faces problems that generally come with have a low immune system.

  1. Higher blood pressure

According to a study conducted, it was seen that elderly person who is lonely has a higher blood pressure than a person who does not feel the stress and problems associated with feeling/being lonely. The study was conducted on the blood pressure of different elderly people over the course of 5 years. To back up the fact that being lonely can raise the blood pressure level, the people in charge of the study also tracked the elderly person’s level of social connection and happiness as well to get a better result. Here it is important to add that having high blood pressure will lead to many different types of heart health problems, eye problems (retinopathy) and kidney diseases among many other such health problems.

  1. Risk of heart diseases

According to many different studies it was confirmed that being isolated is associated with 25 to 30% of people having different heart diseases, heart attack and angina. Based on these studies, it was also seen that 32% of lonely people as result have the risk of stroke as well which means being alone may reduce the life expectancy of a person significantly. Here it should be mentioned that the studies were done both of male and female candidates and the result as almost the same.

  1. Affects the genes

Recently, all the discoveries made by John Cacioppo of University of Chicago shed a new light on the health problems that comes with being lonely. Among many different negative mental and physical effects, it was seen that being lonely are even associated with changed expression of the person’s genes as well which is a ground breaking and concerning discovery. So, it is quite safe to say that being lonely not only comes with the risk of dying, but it may hurt us at the simplest expression of human existence as well.

  1. Sleeping disorder

Being lonely can be a result of being depressed for many, but in some cases being lonely can lead to depression and many other mental diseases as well. In fact, it was proven that it causes the same effect on the person’s brain as a person in physical pain feels. Among all the mental health problems, being lonely plays a huge role in the quality of sleep. It was seen that people who are lonely do have a lot of problem with sleep which result in them dealing with sleeping disorders including insomnia on a regular basis. Not having a proper night’s rest can affect the mood and productivity of a person. So, it can be said that being lonely and dealing with sleeping disorder as a result will hinder a person ability to carry on with his or her daily routine. Besides, not getting proper sleep plays a huge role in worsening the other different symptoms of depression as well.

  1. Risk of Dementia

From loss of memory to inability to focus or pay attention to problems with communication to problems with judgment and reasoning to problems with visual perception; there are far many symptoms and health issues that are associated with dementia. Dementia affects a large number of people, and in most cases the cause of the problem is chronic isolation. It has also been seen that chronic loneliness even aid in rapid progression of Alzheimer’s disease as well. Based on a Dutch study published in the year 2012, it was seen that being lonely leads to this health hazards in people especially elderly people. Even though there are some studies which claims that feeling lonely or becoming isolated is a sign/symptoms of dementia and not the cause., but this not properly proven yet. Nevertheless, it is safe to say that chronic isolation and risk of dealing of dementia goes hand in hand.

Besides these, there are many other dangerous health hazards which are related to chronic loneliness which makes it necessary for a person who is dealing with this to look into it properly or get the required help most earnestly.

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